About the project

Project proposal title:

Domestic animals as experimental models for evaluation of biomaterials compatibility.

Acronym: ANIMBIOCOMP

Project Code: #6417324, ANIMBIOCOMP

ANIMBIOCOMP project belongs to the field of Biomedical research, funded by the Science Fund of the Republic of Serbia within the Serbian science and Diaspora Collaboration Program: Knowledge Exchange Vouchers whose one of the aims is to establish cooperation with the diaspora in order to improve and exchange knowledge, establish or improve cooperation, joint work on scientific research and research and development problems and challenges.

Abstract:

Evaluation of new biomaterials as innovative approach to substitute or upgrade structural components of the organism requires multidisciplinary approach of veterinarians and doctors. Adequate animal model for evaluation of its compatibility in order to estimate risks and advantages in humans is required. The aim of project is to train and enable Serbian scientists to create animal models for evaluation of biomaterials compatibility with experience and supervision of the expert from diaspora.

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Team members

Danijela Kirovski, PI

Contact

PhD Danijela Kirovski, DVM, Full Professor Specialist in Bovine Health Management Department of Physiology and Biochemistry Faculty of Veterinary Medicine, University of Belgrade Bulevar oslobodjenja 18, 11000, Belgrade, Serbia
email: dani@vet.bg.ac.rs

Research field

Metabolism of domestic animals, endocrinology, physiology of domestic animals

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Ljubomir Jovanović

Contact

PhD Ljubomir Jovanović, DVM, Teaching Assistant Department of Physiology and Biochemistry Faculty of Veterinary Medicine, University of Belgrade Bulevar oslobodjenja 18, 11000, Belgrade, Serbia
email: ljubomir.jovanovic@vet.ac.bg.rs


Research field

Metabolism of domestic animals, physiology of domestic animals

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Milica Stojić

Contact

PhD Milica Stojić, DVM, Assistant Professor Department of Physiology and Biochemistry Faculty of Veterinary Medicine, University of Belgrade Bulevar oslobodjenja 18, 11000, Belgrade, Serbia
email: stojicm@vet.bg.ac.rs


Research field

Metabolism of domestic animals, physiology of domestic animals

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Ivan Milošević

Contact

PhD Ivan Milošević, DVM, Assistant Professor Department of Histology and Embryology Faculty of Veterinary Medicine, University in Belgrade Bulevar oslobodjenja 18, 11000, Belgrade, Serbia
email: ikavet@vet.bg.ac.rs


Research field

Veterinary medicine – histology and embryology, pathohistology, biology – cell and molecular biology

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Bogomir Bolka Prokić

Contact

PhD Bogomir Bolka Prokić, DVM, Assistant Professor Department of Surgery, Orthopedy and Ophtalmology Faculty of Veterinary Medicine, University of Belgrade Bulevar oslobodjenja 18, 11000, Belgrade, Serbia
email: bogomirprokic@vet.bg.ac.rs


Research field

Experimental surgery, soft tissue surgery

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Dragan Ristanović

Contact

Dragan Ristanović, DVM, Junior Research Assistant Specialist in Small Animal Orthopedics Department of Surgery, Orthopedy and Ophtalmology Faculty of Veterinary Medicine, University of Belgrade Bulevar oslobodjenja 18, 11000, Belgrade, Serbia
email:dragan.ristanovic@vet.bg.ac.rs


Research field

Small Animal Orthopedics

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Risto Dučić

Contact

Risto Dučić, DVM, Teaching Assistant Department of Surgery, Orthopedy and Ophtalmology Faculty of Veterinary Medicine, University of Belgrade Bulevar oslobodjenja 18, 11000, Belgrade, Serbia
email: risto.ducic@vet.bg.ac.rs


Research field

Experimental surgery, veterinary orthopedic

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Vladimir Bubalo

Project Partner from diaspora
Contact

PhD Vladimir Bubalo, Dr.med.vet., Senior Research Associate Division of Biomedical Research at Medicine University of Graz Roseggerweg 48, Graz, Austria
email: vladimir.bubalo@klinikum-graz.at


Research field

Biomedical research of small, large and laboratory animals, veterinary anaesthesia

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Activities

Trainings of Serbian SRO scientists at Host institution in the field of biomaterials compatibility experiments

The researchers from Serbian SRO will be trained at Host institution to design and implement experiments on domestic animals used as models in biomaterials compatibility estimating in preclinical scientific researches. Besides learning the basic principles of working with different species of animals and planning the experiments, the Serbian team will be introduced to the up-to-date methodology used in current research in biomaterials used in surgical procedures. Researchers from SRO will learn how to perform surgical procedures and postoperative monitoring of the animals with biomaterials implants. Also, molecular techniques on tissue acquired from different species of domestic animals will be tested. As overall result of activity 1. staff from Serbian SRO will be trained for conducting biomaterials compatibility experiments on laboratory and conventionally raised animals (pigs and sheep).

Developing of “Experimental facility for conventionally raised animals” at Serbian SRO

The aim of the project is to establish a new “Experimental facility for conventionally raised domestic animals (pigs and sheep)” at Serbian SRO. Registration will be conducted at the Serbian Ministry of Agriculture, Forestry and Water Economy. The “Experimental facility for conventionally raised animals (pigs and sheep)” will be adopted in consultation with expert from diaspora in accordance with 3R Directive 63/2010EU and good practice in the Host institution. Serbian SRO will finance the adaptation of Experimental facility (one room for pigs and one for sheep) as strong contribution to the project implementation.

Dissemination of project activities and results

As overall result of activity 3. the project outputs will be presented to the public including promotion of project activities and results at scientific conferences and preparing of project promo materials. After every training at the Host institution, report containing photographs will be published at the website. The key result of activity 3. will be the promotion of the newly established “Experimental facility for conventionally raised animals” to scientific public. This should lead to recognition of Serbian SRO as unique center for biomaterials compatibility experiments on pigs and sheep in the region.

Results and reports